Fig. 16

Scatter plots of gene pairs with significant interactions for the lung cancer dataset. Blue denotes patients who survived for at least sic years after diagnosis (low risk) and red denotes patients who died or relapsed within six years (high risk). It seems: (a) for a subpopulation of high risk patients BCLAF1 has decreased expression and ILF3 is over-expressed, (b) decreased expression of LAMC2 and CDH3 is an indicator of low risk, decreased expression of LAMC2 and over-expression of CDH3 is an indicator of “medium” risk, and over-expression of both is an indicator of high risk, (c) decreased expression of BCLAF1 or SOS2 compared with each other is an indicator of high risk, and (d) decreased expression of CDH3 is an indicator of low risk, over-expression of CDH3 and low expression of ANXA1 is an indicator of high risk, and over-expression of both results in medium risk