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Table 2 Estimated power (%) under 2.8×10−6 significance level for different tests. Data are simulated from N(A×△,R). A has 3 nonzero elements with different signs

From: TS: a powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data

nonzero â–³

nonzero A

AT

S2T

ST

GATES

aSPU

TS

(4,2,1)

(1,1,1)

68.0

8.5

68.5

16.5

83.5

95.5

(4,4,2)

(1,1,-1)

69.0

45.0

45.0

28.5

65.6

93.8

(2,5,4)

(1,-1,-1)

92.5

74.5

76.0

65.5

62.0

98.2

U(1,5)

(1,1,1)

86.0

37.0

87.0

24.0

86.0

97.8

U(2,6)

(1,1,-1)

71.5

71.5

19.0

58.0

68.0

92.0

U(2,6)

(1,-1,-1)

70.0

70.5

19.5

65.5

64.5

92.5

N(3,4)

(1,1,1)

83.0

60.0

83.5

74.5

88.5

95.5

N(3,4)

(1,1,-1)

68.0

70.0

33.0

72.5

69.5

85.7

N(3,4)

(1,-1,-1)

66.0

61.5

33.0

78.0

73.5

87.1