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Table 3 Comparison of the four methods using the PGC SCZ and UKB T2D GWAS summary data

From: TS: a powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data

Methods

aSPU

GATES

GW

TS

  

PGC SCZ

  

Total significant genes (m,%)

76 (31, 40.8%)

73 (23, 31.5%)

93 (32, 34.4%)

215 (43, 20%)

Unique significant genes (u,%)

4 (1, 25%)

14 (0, 0%)

15 (1, 6.7%)

155 (13, 8.4%)

  

UKB T2D

  

Total significant genes (m,%)

54 (25, 46.3%)

40 (12, 30%)

57 (27, 47.4%)

217 (47, 21.7%)

Unique significant genes (u,%)

0 (0, 0%)

7 (1, 14.3%)

1 (0, 0%)

155 (17, 11%)

  1. Note: m denotes the number of significant SNPs in GWAS and u denotes the number of significant SNPs in GWAS. GW denotes a combination of ST, S2T, and AT.