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Fig. 5 | BMC Bioinformatics

Fig. 5

From: SCeQTL: an R package for identifying eQTL from single-cell parallel sequencing data

Fig. 5

P-value distribution under null hypothesis of (a) SCeQTL and (b) Matrix eQTL. c An example that non-zero part of gene expression have significant differences among genotype groups. d The non-zero part of an example of significant zero-ratio differences. Zero-ratio of three genotype groups are 0.76, 0.26 and 0.26, respectively. We can see from the figure that the non-zero expressions are not associated with the genotype, but the zero-ratios are. These findings will be not significant for Matrix eQTL after multiple test correction, but are very significant for SCeQTL

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