Fig. 12

Histogram of simulated data underlying the prediction of cell pool compositions in Fig. 13a: 100 synthetic 5-cell measurements arising from the LN–LN model with two populations with parameters \(\varvec{p}=(0.2,0.8),\,\varvec{\mu }=(2,0)\,\text{and}\,\,\sigma =0.2\). The PDF with true model parameters is shown in orange, the PDF with estimated parameters \(\varvec{\hat{p}}=(0.14, 0.86),\,\varvec{\hat{\mu }}=( 2.04, 0)\,\text{and}\,\hat{\sigma }= 0.20\) in blue