Skip to main content

Table 1 A comparison of features between SomatoSim and existing somatic variant simulation tools

From: SomatoSim: precision simulation of somatic single nucleotide variants

  SomatoSim VarSim SInC DWGSIM GemSim tHapMix Xome-Blender BAMSurgeon
Variants introduced into experimentally generated reads X X X X
User definable VAFs X X X X X
User definable depth of coverage X
MQ and BQ control X X X X X X X
User definable separation distance between randomly simulated SNVs X X X X X X X
Strand distribution modeling X X X X X X X
Types of somatic variants SNV SNV, Indel, SV SNV, Indel, CNV SNV, Indel SNV SNV, CNV SNV, Indel, CNV SNV, Indel, CNV, SV
Output data type BAM FASTQ FASTQ FASTQ FASTQ BAM BAM BAM