Fig. 4

PIGNON identifies different GO terms than the NEA and MCL-Ontologizer approaches. Venn diagrams comparing the overlap of significant GO terms identified by PIGNON against the MCL-Ontologizer or NEA approach comparing the a, b HER2+/TN (PIGNON FDR < 0.001; MCL-Ontologizer FDR adjusted-p < 0.001; NEA FDR < 0.001), c, d HR+/TN (PIGNON FDR < 0.0029; MCL-Ontologizer FDR adjusted-p < 0.0029; NEA FDR < 0.0029), and e, f HER2+/HR+ (PIGNON FDR < 0.0013; MCL-Ontologizer FDR adjusted-p < 0.0013; NEA FDR < 0.0013) subtypes at comparable confidence thresholds