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Fig. 4 | BMC Bioinformatics

Fig. 4

From: PIGNON: a protein–protein interaction-guided functional enrichment analysis for quantitative proteomics

Fig. 4

PIGNON identifies different GO terms than the NEA and MCL-Ontologizer approaches. Venn diagrams comparing the overlap of significant GO terms identified by PIGNON against the MCL-Ontologizer or NEA approach comparing the a, b HER2+/TN (PIGNON FDR < 0.001; MCL-Ontologizer FDR adjusted-p < 0.001; NEA FDR < 0.001), c, d HR+/TN (PIGNON FDR < 0.0029; MCL-Ontologizer FDR adjusted-p < 0.0029; NEA FDR < 0.0029), and e, f HER2+/HR+ (PIGNON FDR < 0.0013; MCL-Ontologizer FDR adjusted-p < 0.0013; NEA FDR < 0.0013) subtypes at comparable confidence thresholds

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