A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation

BMC Bioinformatics

Table 3 Markers of the phases of the circadian clock

Phase	Marker	Compartment
RORG	RORG	Nucleoplasm
SIRT1	SIRT1	Nucleoplasm
ARNTL-CLOCK	ARNTL(Ac@L538\|P@S90):CLOCK(ADPr):CSNK2A	Nucleoplasm
PER-CRY	PER1:CRY1:CRY2:ARNTL(Ac@L538\|P@S90): CLOCK(ADPr):PER2(Ac):CSNK1D:CSNK1E	Nucleoplasm

The markers for each phase of the cell cycle are given under a textual form. The names used to describe the markers are the labels of the corresponding entities in the map. Subunits in complexes are separated using the “:” character. Text in parantheses gives the post-translational modifications of a given entity (protein or complex subunit). For example, “P@Thr172” represents a phosphorylation at threonine 172. A same entity may have more than one post-translational modifications, separated in the text by the “|” character

ISSN: 1471-2105