Fig. 11
From: Comparative evaluation of full-length isoform quantification from RNA-Seq
Method effect on differential expression analysis, using realistic data. The roughly 43,872 isoforms with zero true expression in both Liver and Hippocampus, serve as a set of null isoforms for the DE analysis. A Gives a lower bound on the true FDR of the isoforms rejected at each q-value cutoff. Plots above the black line are anti-conservative. B Same as A but shows the actual number of null isoforms determined DE as a function of the q-value. Note that only 94,929 isoforms exist in total