Fig. 4

The interpretation and application example of the ‘NuP Browser’ module. a The operation and results exhibition of the ‘NuP Browser’ module. b The average nucleosome profile of positive samples or negative samples in ELF1 binding prediction model in the GM12878 cell line. The red line represents the ELF1 motif hits overlapping with ChIP-seq peaks. The orange line represents the ELF1 motif hits that not overlap with ChIP-seq peaks. c The ROC curve and AUC score for the ELF1 prediction model. The orange line represents the prediction performance of the model with only motif scores. The blue line represents the prediction performance of the model that includes nucleosome organization features. d The practical TF binding status and prediction results of ELF1 in the GM12878 cell line. Two examples failed to be recognized by the prediction model with only motif scores but were recognized after nucleosome organization features introduction