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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing

Fig. 4

Algorithm performance comparing mcCNV and ExomeDepth. a–c mcCNV versus ExomeDepth with default parameters, 1/10, 000 transition probability and 50 kb expected variant length. d–f mcCNV versus ExomeDepth with simulation-matched parameters, 1/1000 transition probability and 1 kb expected variant length. Numbered points indicate the simulated depth in millions of molecules. ‘MCC’ indicates Matthew’s correlation coefficient; ‘TPR’ indicates true positive rate/sensitivity; ‘FDR’ indicates false discovery rate. Dashed black line shows the 1:1 relationship

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BMC Bioinformatics

ISSN: 1471-2105

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