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Table 1 Summary of whole-exome sequencing. ‘pool’ indicates the name of the pool of samples; ‘capture’ indicates the capture platform for the pool; ‘N’ gives the number of samples in the pool; ‘medExon’ gives the pool median of the subject median mapped molecule count per exon; ‘medTotal’ gives the median by pool of total mapped molecule counts per subject; ‘minTotal’ and ‘maxTotal’ give the minimum and maximum total mapped molecules; ‘rsdTotal’ gives the relative standard deviation (SD/mean*100) of total mapped molecules

From: Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing

Pool Capture N medExon medTotal minTotal maxTotal rsdTotal
IDT-ICa IDT 16 143 55,149,058 37,453,015 85,138,915 22.4
IDT-MC IDT 16 93 29,772,684 16,674,468 118,147,912 64.2
IDT-RR IDT 16 272 79,079,629 61,289,322 120,147,888 22.9
NCGENESa Agilent 112 93 24,451,245 12,749,793 68,565,471 27.6
Pool1 Agilent 16 56 13,265,614 8,911,132 17,324,903 18.5
Pool2 Agilent 16 86 21,076,056 4,585,195 27,846,146 27.6
SMA1 Agilent 8 56 12,256,002 11,051,840 13,600,697 6.2
SMA2 Agilent 8 25 5,622,040 4,904,000 6,545,360 10.4
WGS Agilent 16 196 46,406,224 36,496,097 65,200,410 16.4
  1. aIndicates captures were performed independently on each sample within the pool, otherwise captures were multiplexed across all samples within the pool