Fig. 8
From: PhyliCS: a Python library to explore scCNA data and quantify spatial tumor heterogeneity
Test case: breast tumor data. We tested PhyliCS on a scCNA dataset containing the data of five sections (S_A, S_B, S_C, S_D, S_E) of the same breast tumor. After some preliminary operations, we discarded S_A and kept the others for further analysis. We obtained the evidence that the sections share similar genomic patterns (a), with the exception of S_B; this is confirmed by the SHscore (b), which best value (0.1824) is obtained by by aggregating S_C, S_D, S_E against S_B