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Table 7 Number of essential proteins predicted by TGSO and 13 methods based on the Gavin database

From: An iteration model for identifying essential proteins by combining comprehensive PPI network with biological information

Methods Top1% (19) Top5% (93) Top10% (196) Top15% (279) Top20% (371) Top25% (464)
SC 0 17 87 130 190 240
EC 0 38 94 134 166 209
BC 9 40 85 122 162 201
DC 7 36 101 158 222 264
IC 16 55 119 163 213 254
CC 11 45 93 135 180 221
NC 11 51 123 170 213 259
PEC 15 69 142 193 238 285
CoEWC 16 69 136 190 237 275
POEM 17 74 148 199 249 296
ION 17 73 150 207 263 312
CVIM 16 80 160 219 271 322
TGSO 19 81 165 221 279 332
  1. This table shows the commonalities and differences between TGSO and the 13 competitive methods in Table 1 based on the Gavin database