Fig. 5

Physical interactions often occur among drug target proteins and proteins encoded by genes with the highest weight (\(weight=1\)). a Five BRAF inhibitors were included in the training data. Genes with \(weight=1\) were extracted from the gene weight layer after model training, and their interactions with BRAF were analyzed in the String database. Connections within 2 degrees from BRAF were shown, grouped by drug. b Three BCL2 inhibitors was included in the training data. Analysis procedure was the same as above. The network showed connections within 2 degrees from BCL2