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Table 1 Boolean truth tables for both activating and inhibiting gene interactions

From: Boolean factor graph model for biological systems: the yeast cell-cycle network

Activation

Inhibition

\(x_{1}\)

\(x_{2}\)

\(x_{2}^{\prime }\)

\(x_{1}\)

\(x_{2}\)

\(x_{2}^{\prime }\)

0

0

0

0

0

0

0

1

1

0

1

1

1

0

1

1

0

0

1

1

1

1

1

0

  1. Column \(x_{1}\) represents the state of a regulator node, and column \(x_{2}\) denotes the child node state at time t. The output state of the child node at time \(t+1\) is denoted by column \(x_{2}^{\prime }\). For activation, \(x_{2}^{\prime } = x_{1} \vee x_{2}\), and for inhibition, \(x_{2}^{\prime } = (x_{1} \oplus x_{2}) \wedge x_{2}\). Only when a parent node is active does it contribute information to the child node