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Table 2 Effects of sequence identity on the performance of CirPred

From: CirPred, the first structure modeling and linker design system for circularly permuted proteins

Sequence identitya (%) Alignment ratiob (%) RMSDb (Å) Number of CP pairs
90–100 97.6 1.236 79
80–90 95.7 1.673 39
70–80 94.7 1.504 8
60–70 95.1 3.124 10
50–60 96.7 1.910 31
40–50 98.7 2.002 236
30–40 98.1 2.026 351
20–30 90.9 2.496 161
10–20 74.0 3.904 653
  1. In this experiment, for each pair of circular permutants, one protein was utilized as the template to create the model of the other protein, i.e., the target
  2. aSequence identities between the template and target proteins
  3. bAlignment ratio and RMSD values between the model and known structure of target proteins