Fig. 2
From: CoolBox: a flexible toolkit for visual analysis of genomics data

Joint (2d) view example, CoolBox can compose big figure which put frames around a center contact matrix. This allows to visualize the trans or cis remote (off-diagonal) contact matrix along with genome features. A Joint view on an on-diagonal region. B Joint view on an cis remote region, which shows the magnified detail of the orange box marked loop region that contains two chromatin loops in (A)