Using multi-layer perceptron to identify origins of replication in eukaryotes via informative features

BMC Bioinformatics

Table 1 Comparison of prediction methods based on training dataset

Species	Methods	Acc (%)	Sn (%)	Sp (%)	MCC	AUC
H. sapiens	Ours	92.60	91.16	94.16	0.8677	0.9983
H. sapiens	Wei et al. [9]	88.30	89.60	87.00	0.7660	0.9560
M. musculus	Ours	90.80	89.38	92.21	0.8280	0.9821
M. musculus	Wei et al.	89.10	87.50	90.70	0.7662	0.9558
D. melanogaster	Ours	91.22	91.53	90.89	0.8219	0.9876
D. melanogaster	Wei et al.	88.60	85.90	91.20	0.7720	0.9470
A. thaliana	Ours	96.15	97.07	95.17	0.9155	0.9963
A. thaliana	Wei et al.	94.09	93.79	93.50	0.8729	0.9817
P. pastoris	Ours	94.20	92.36	95.76	0.8953	0.9678
P. pastoris	Dao et al. [8]	88.38	87.69	89.00	0.7669	0.9500
S. pombe	Ours	99.86	100	100	1	0.9985
S. pombe	Dao et al.	99.85	100	99.71	0.9971	0.9945
K. lactis	Ours	96.72	97.36	96.19	0.9251	0.9965
K. lactis	Dao et al.	93.75	94.12	93.50	0.8715	0.9781

ISSN: 1471-2105