Fig. 1
From: Filling gaps of genome scaffolds via probabilistic searching optical maps against assembly graph
A case study of gap filling using OMACC and nanoGapFiller. For the the gap 781738-781976r of S. coelicolor, there are two contig paths connecting the beginning site and ending site: one path contains the contig 777124 while the other path contains its reverse complement 777124r. OMACC explores the distance between the beginning site and ending site only, and thus cannot identify which path matches better with the corresponding optical map. In contrast, nanoGapFiller utilizes the enzyme recognition sites in the intermediate contig 777124 and 781726r and thus correctly identified the contig path that fills the gap (shown in red)