Fig. 6
Visualisation of the methylation patterns of robust significant methylation features that were consistently identified by LRSC. A visualisation of the methylation patterns of the 233 significant methylation features consistently identified across all ten runs by LRSC. Cluster labels were taken from the best run of LRSC as determined by log-rank P-value. Methylation is shown as a z-score. Scale was limited to − 3 + 3 using vmin and vmax in the clustermap function in Seaborn to improve visualisation of differences between prognostic clusters. The distribution of HCC grades between clusters appears to be relatively even