Fig. 5
![Fig. 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12859-021-04477-x/MediaObjects/12859_2021_4477_Fig5_HTML.png)
Dose–response diagram exhibiting switch-like behavior produced by a futile signaling cycle. Dots represent the equilibrium that the system converges to for individual simulations. The red and light blue paths correspond to high and low initial concentrations of \([S^*]\), respectively