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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

Fig. 4

Exploration of impact of proportionality constant on predicted flux in anaerobic and aerobic in S. cerevisiae (Rintala dataset): A growth, B aerobic ethanol secretion, C anaerobic ethanol secretion. Data from growth simulations (A) are used to identify optimal values for the proportionality constant as those for which model predictions match experimental values (40.6 and 86.56 for anaerobic and aerobic strains respectively). Simulations of ethanol production (B and C) are done by fixing the fitted values followed by sampling of the solution space. The error bars indicate the standard deviations

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