Skip to main content
Fig. 1 | BMC Bioinformatics

Fig. 1

From: STRIDE: a command-line HMM-based identifier and sub-classifier of Plasmodium falciparum RIFIN and STEVOR variant surface antigen families

Fig. 1

General structure of RIFINs and STEVORs. RIFINs and STEVORs are expressed on the surface of an erythrocyte infected with P. falciparum. Protein domains are illustrated as green (signal peptide), grey (variable domains), red (transmembrane domains), blue (25 amino acid insertion), and orange and purple (semi-conserved domains). There are approximately 160 rif genes in the 3D7 reference genome, separated into two subtypes, RIFIN-A and RIFIN-B, depending on sequence and subcellular localization. The FHEYDER motif (in blue) is present in the semi-conserved domain of 36 RIFIN-As in the 3D7 reference strain. STEVORs encompass ~ 30 genes per genome and are structurally similar to RIFIN-Bs

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us