Gene prediction of aging-related diseases based on DNN and Mashup

BMC Bioinformatics

Table 8 Evidence of 15 genes recommended for association with disease

Gene ID	Genes associated with “Disease.Immune”	Relevant evidence
3553	IL1B—interleukin 1 beta	Roghieh Safari et al. [26]
1544	CYP1A2—cytochrome P450 family 1	Klein et al. [31]
	subfamily A member
4023	LPL—lipoprotein lipase	S. aureus et al. 2015 [32]
1543	CYP1A1—cytochrome P450 family 1	Uno et al. [33]
	subfamily A member 1
4846	NOS3—nitric oxide synthase 3	Bogdan et al. [34]
Gene ID	Genes associated with “Disease.Brain ”	Relevant evidence
1544	CYP1A2—cytochrome P450 family 1	Siokas et al. [35]
	subfamily A member 2
1559	CYP2C9—cytochrome P450 family 2	Sun et al. [36]
	subfamily C member 9
1586	CYP17A1—cytochrome P450 family 17	Emanuelsson et al. [37]
	subfamily A member 1
338	APOB—apolipoprotein B	Bjelik et al. [38]
1557	CYP2C19—cytochrome P450 family 2	Ingelman-Sundberg et al. [39]
	subfamily C member 19
Gene ID	Genes associated with “Disease.Nutrition”	Relevant evidence
3553	IL1B—interleukin 1 beta	Norde et al. [40]
1544	CYP1A2—cytochrome P450 family 1	Agúndez et al. [41]
	subfamily A member 2
1557	CYP2C19—cytochrome P450 family 2	None
	subfamily C member 19
4035	LRP1—LDL receptor related protein 1	Masson et al. [42]
2688	GH1—growth hormone 1	Thissen et al. [43]

ISSN: 1471-2105