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Table 6 The computational process for measuring the IC of term set S

From: A novel gene functional similarity calculation model by utilizing the specificity of terms and relationships in gene ontology

Step

Term

IC

\(IC_{own}\)

IC(S)

1

\(t_1\)

0.0

0

0.000

2

\(t_2\)

0.01

\(IC_{own}(t_2)=IC(t_2)-IC(t_1)*\omega _{12}=0.01\)

0.010

3

\(t_3\)

0.02

\(IC_{own}(t_3)=IC(t_3)-IC(t_1)*\omega _{13}=0.02\)

0.030

4

\(t_4\)

0.04

\(IC_{own}(t_4)=IC(t_4)-IC(t_2)*\omega _{24}-IC(t_3)*\omega _{34}=0.014\)

0.044

5

\(t_5\)

0.05

\(IC_{own}(t_5)=IC(t_5)-IC(t_3)*\omega _{35}=0.036\)

0.080

6

\(t_6\)

0.07

\(IC_{own}(t_6)=IC(t_6)-IC(t_4)*\omega _{46}=0.044\)

0.124

7

\(t_7\)

0.09

\(IC_{own}(t_7)=IC(t_7)-IC(t_4)*\omega _{47}-IC(t_5)*\omega _{57}=0.026\)

0.150

8

\(t_8\)

0.18

\(IC_{own}(t_8)=IC(t_8)-IC(t_6)*\omega _{68}-IC(t_7)*\omega _{78}=0.058\)

0.208