Efficient link prediction in the protein–protein interaction network using topological information in a generative adversarial network machine learning model

Table 3 Comparisons of the results from Table 2, presenting q-values from Mann–Whitney–Wilcoxon tests

Species	Adjacency only–combined			Adjacency only–embedding only
Species	AUROC	AUPRC	NDCG	AUROC	AUPRC	NDCG
Homo sapiens	0.297	0.577	0.579	< 0.001	< 0.001	< 0.001
Saccharomyces cerevisiae	0.971	0.631	0.631	< 0.001	< 0.001	< 0.001
Mus musculus	0.523	0.796	0.688	< 0.001	< 0.001	< 0.001
Rattus norvegicus	0.228	0.481	0.475	< 0.001	< 0.001	< 0.001
Sus scrofa	0.429	0.429	0.290	< 0.001	< 0.001	< 0.001
Mean	0.490	0.583	0.533	< 0.001	< 0.001	< 0.001

AUROC: area under the receiver operating characteristic curve; AUPRC: area under the precision-recall curve; NDCG: normalized discounted cumulative gain; Combined: adjacency matrices concatenated with embedding vector-based matrices as input

ISSN: 1471-2105