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Fig. 4 | BMC Bioinformatics

Fig. 4

From: CAISC: A software to integrate copy number variations and single nucleotide mutations for genetic heterogeneity profiling and subclone detection by single-cell RNA sequencing

Fig. 4

Evaluation of clustering accuracy using ARI on GSE73122 whose clone types are known. A ARI values show the integration performance of CAISC compared to CNV and SNV approaches. B Fan dendrograms showing the clustering results with SNV, CNV, and integrated approaches. C The tanglegram compares the phylogenetic clustering based on SNV and CNV profiles. Cells in clones defined by SNV also appear in the same clones defined by CNV. The cophenetic correlation between the two clustering results is 0.61

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BMC Bioinformatics

ISSN: 1471-2105

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