Table 17 Top 10 pairs of drugs with their correlation with subtype 5 of breast cancer, considering both combined and individually
From: Computationally repurposing drugs for breast cancer subtypes using a network-based approach
Drug1 | Drug2 | C. Cor. | Cor. 1 | Cor. 2 | C. Rank | Rank 1 | Rank 2 |
|---|---|---|---|---|---|---|---|
TG-100801 | Phensuximide | − 0.97 | − 0.72 | − 0.63 | 1 | 6 | 28 |
Ruxolitinib | Phensuximide | − 0.89 | − 0.93 | − 0.63 | 2 | 1 | 28 |
Ruxolitinib | AMG-837 | − 0.89 | − 0.93 | − 0.83 | 3 | 1 | 2 |
AMG-837 | Phensuximide | − 0.89 | − 0.83 | − 0.63 | 4 | 2 | 28 |
Ruxolitinib | Citrulline | − 0.89 | − 0.93 | − 0.82 | 5 | 1 | 3 |
Amikacin | Tadalafil | − 0.88 | − 0.59 | − 0.57 | 6 | 47 | 65 |
L-citrulline | PD-153035 | − 0.88 | − 0.82 | − 0.62 | 7 | 3 | 35 |
Ruxolitinib | AMG-232 | − 0.88 | − 0.93 | − 0.56 | 8 | 1 | 73 |
Bardoxolone-methyl | AP-26113 | − 0.88 | − 0.63 | − 0.58 | 9 | 33 | 52 |
Ruxolitinib | Bisoprolol | − 0.88 | − 0.93 | − 0.71 | 10 | 1 | 8 |