Fig. 11
From: De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet
Multi-omics deregulated subgraph showing consistent methylation-transcription patterns. Inner node color represents RNA-Seq log2 fold change while the rim color of a node represents the methylation score \(m_v\) where red corresponds to upregulated methylation and blue corresponds to downregulated methylation. The color of edges indicates the following interactions: activation (red), compound (brown), binding/association (yellow), indirect effect (dashed grey) and expression (green)