Fig. 1
From: SPINNAKER: an R-based tool to highlight key RNA interactions in complex biological networks
SPINNAKER conceptual organization. [Left] Algorithm steps. [Top right] Comparison of ceRNA predictions obtained by SPINNAKER, when applied to breast cancer dataset [13], with respect to other statistics-based methods in identifying experimentally confirmed and breast cancer related ceRNA interactions, defined as those in which the two interacting ceRNAs are breast cancer related genes [11]. [Bottom right] Example of ceRNA interactions predicted by SPINNAKER in breast normal tissues from breast cancer dataset [13]. Scatter plots of the ceRNA expression levels (log2-scale) in normal (blue dots) and cancer (orange dots) tissues; r = Pearson correlation coefficient, p = p-values