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Table 1 Overall prediction accuracy, binding energy and running time comparison of Vina, PSOVina, GWOVina MPSOVina and MRDPSOVina

From: Parallel multi-swarm cooperative particle swarm optimization for protein–ligand docking and virtual screening

  Mean RMSD (Å) Mean succ (%) Mean energy a P-value b Mean time (s)
Vina 2.521 ± 0.328 64.35 − 8.680 2.73e-10 39.77
PSO-c4 2.283 ± 0.262 66.67 − 8.402 0.081 8.17
PSOVina 2.787 ± 0.274 59.47 − 8.274 3.99e-9 3.91
GWOVina 2.411 ± 0.317 65.72 − 8.671 2.87e-11 8.25
MPSOVina 2.133 ± 0.264 70.53 − 8.594 0.27 4.27
MRDPSO-c4 2.189 ± 0.272 69.75 − 8.572 0.0015 6.08
MRDPSOVina 2.056 ± 0.259 71.05 − 8.607 4.28
  1. aThe unite of mean binding energy is Kcal mol−1
  2. bP-value is calculated by comparing two sets of mean RMSD results obtained by the MRDPSOVina and another docking method, respectively