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Table 5 Davis \(\cap\) sc-PDB Binding Sites - \(L_{Grad-RAM}\) matching results (Eq. 8) across different window lengths and for the different formulations of the \(L_{Grad-RAM}\), where lower and higher percentage values are associated with lower and higher number of window-based binding pockets where information is being extracted from at least one position across all the DTI pairs, respectively

From: Explainable deep drug–target representations for binding affinity prediction

Window length

GMP-G

GMP-NG

GAP-G

GAP-NG

0

20.74

20.74

20.74

19.57

1

46.32

46.32

46.32

42.83

2

53.29

53.29

53.29

50.39

3

56.98

56.98

56.98

54.07

4

60.66

60.66

60.66

57.95

5

61.24

61.24

61.24

58.72

  1. GMP, global max pooling; GAP, global AVG pooling; G, guided gradients; NG, non guided gradients