Fig. 5
From: A hierarchical spike-and-slab model for pan-cancer survival using pan-omic data
Figure 5a displays a KDE plot for component 11.1 within each of the KIRP subtypes, showing CIMP subjects clustering distinctly along component 11.1. This pattern of variation was identified as predictive of survival in KIRP as well as KIRC subjects. Figure 5b shows a Kaplan–Meier survival plot for all KIRP and KIRC subjects, showing KIRP subjects with the CIMP subtype have the poorest survival. Though KIRC does not currently have a known CIMP subtype, the clinical significance of this subtype is well-known for KIRP. Our analysis suggests a similar distinction may exist in KIRC that is also clinically relevant