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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Locality-sensitive hashing enables efficient and scalable signal classification in high-throughput mass spectrometry raw data

Fig. 1

Experimental workflow in an LC-IMS-MS setup and resulting signal of interest. a Chemical separation by high-performance liquid chromatography (HPLC) and resulting intensity distribution along retention time. b Subsequent ion-mobility separation (IMS) and resulting intensity distribution along the mobility dimension. c Time-of-flight mass spectrometry (TOF-MS) and resulting isotopic pattern, i.e., evenly spaced peaks with a certain distribution of the peaks envelope. The column on the right shows the signal as a function of two variables, drift time and retention time on the top and mass-over-charge ratio and drift time on the bottom. Note the repeated occurrence of these isotopic patterns in the 3D plot on the bottom right

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