Table 4 Genes with ABCG2 direct interaction and the confidence of the regulation (w) determined by IntOMICS
From: Using empirical biological knowledge to infer regulatory networks from multi-omics data
5FU/FA | FOLFIRI | |||
|---|---|---|---|---|
Low-RFS | High-RFS | Low-RFS | High-RFS | |
ELK1 | High | Med | Low | Med |
HRAS | Low | Med | Low | High |
MAP3K1 | High | Med | Low | NA |
MAP2K1 | Med | High | NA | Low |
MAPK1/ERK2 | Low | Low | Med | High |
MAPK3/ERK1 | High | Low | Low | NA |
MRAS | Low | Low | High | Low |
MYC | High | Med | Med | Med |
MYCN | Low | Low | Low | High |
RAF1 | Med | NA | Low | High |
RPS6KA3 | High | NA | NA | Low |
ABCG2 CNV | High | High | High | High |