| Annotation enrichment |
---|
Strongly | Moderately | Weakly | Unenriched |
---|
SNP effect class |
Large | 5 | 2 | – | – |
Medium | 300 | 100 | 20 | – |
Low/null | 150 | 300 | 400 | 450 |
Scenario |
A | 1 | 1 | – | – |
B | 1 | 1 | 1 | 1 |
C | – | 2 | 1 | 1 |
D | 2 | 2 | 3 | 2 |
- We defined 4 levels of non-null SNP enrichment for simulated annotations (top part of the table) that can be mixed and matched to construct various scenarios (bottom part of the table). The top part shows the number of SNPs of each size effect class (rows) used to construct each level of annotation enrichment (columns). The bottom part indicates the number of each type of annotation enrichment (columns) used to construct each scenario (rows)