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Table 2 Key pathways associated with the long-term survival in multiple cancers

From: Risk stratification and pathway analysis based on graph neural network and interpretable algorithm

Pathway

Cancer

IG scorez

Aberrant regulation of mitotic cell cycle due to RB1 defects

LUAD

2.161

Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects

LUAD

3.153

E3 ubiquitin ligases ubiquitinate target proteins

LUAD

3.100

Regulation of RUNX3 expression and activity

LUAD

2.372

Signaling by ERBB4

SKCM

3.628

Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects

KIRC

3.523

Signaling by FGFR

KIRC

3.525

Stabilization of p53

KIRC

1.970

Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects

LGG

4.955

Regulation of TP53 Expression and Degradation

LGG

3.927

  1. IG scorez indicated the importance of the pathway in predicting clinical risk classification, and the larger the value the higher the importance