Skip to main content
Fig. 3 | BMC Bioinformatics

Fig. 3

From: Single object profiles regression analysis (SOPRA): a novel method for analyzing high-content cell-based screens

Fig. 3

Results of SOPRA regression analysis and cluster profiles. A Calculated RSQ and p-values of each well for the features ‘Area’, ‘Mean Intensity DAPI’, and ‘Total Intensity DAPI’ using the maSigPro package. B Data visualization by cluster analysis. Normalized distribution profiles of all significantly altered normalized profiles for the three image features were clustered using k-means with 4, 3 and 2 clusters, respectively. The average feature profile is shown (black line) together with the individual profiles of the cell populations in the cluster (grey lines) or C as the mean of 3 replicates

Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us