GMMchi: gene expression clustering using Gaussian mixture modeling

BMC Bioinformatics

Table 2 Top 50 genes significantly associated with MUC2: genes positively correlated with MUC2 in 78 colorectal cancer cell lines

MUC2	−/−	−/+	+/−	+/+	p value	r-value
REG4_weighted	51	12	1	14	1.17E−07	0.62
FCGBP	50	13	2	13	3.27E−06	0.55
SPINK4	52	11	4	11	6.36E−05	0.49
ST6GALNAC1	39	24	0	15	1.15E−05	0.49
SLC39A5-2	61	2	9	6	4.34E−04	0.48
IGK /// IGKC-4	63	0	11	4	9.57E−04	0.48
TFF1	51	12	4	11	1.14E−04	0.47
RETNLB-1	57	6	7	8	4.63E−04	0.45
nan-983	47	16	3	12	1.47E−04	0.45
AZGP1-1	43	20	2	13	2.18E−04	0.44
FAM3D	52	11	5	10	3.72E−04	0.44
NOSTRIN	34	29	0	15	6.71E−05	0.43
RSPH1	42	21	2	13	2.68E−04	0.42
LRRC19	56	7	7	8	8.98E−04	0.42
SULT1B1	61	2	10	5	2.34E−03	0.42
GPD1-4	63	0	12	3	5.98E−03	0.41
MMP28-5	62	1	11	4	4.22E−03	0.40
RETNLB-2	62	1	11	4	4.22E−03	0.40
SEC16B-3	62	1	11	4	4.22E−03	0.40
AMN-2	62	1	11	4	4.22E−03	0.40
nan-6995	62	1	11	4	4.22E−03	0.40
CYP3A5-1	31	32	0	15	2.26E−04	0.40
DDC_weighted	31	32	0	15	2.26E−04	0.40
CFTR-1	31	32	0	15	2.26E−04	0.40
VDR-2	30	33	0	15	2.83E−04	0.39
AKR1C3	30	33	0	15	2.83E−04	0.39
C2orf89	30	33	0	15	2.83E−04	0.39
AGR3	39	24	2	13	1.04E−03	0.38
DACH1-1	39	24	2	13	1.04E−03	0.38
ATP8B1-2	29	34	0	15	5.99E−04	0.38
CEACAM5-1	29	34	0	15	5.99E−04	0.38
PPARA-7	29	34	0	15	5.99E−04	0.38
ETS2-1	29	34	0	15	5.99E−04	0.38
PPARA-6	29	34	0	15	5.99E−04	0.38
PAPSS2-2	34	29	1	14	9.92E−04	0.37
FOXA2_weighted	34	29	1	14	9.92E−04	0.37
IHH-2	34	29	1	14	9.92E−04	0.37
ENTPD5-2	54	9	7	8	2.77E−03	0.37
UGT1A8 /// UGT1A9	54	9	7	8	2.77E−03	0.37
LGALS9	42	21	3	12	1.37E−03	0.37
TMED6	60	3	10	5	5.52E−03	0.37
NOX1-1	38	25	2	13	1.27E−03	0.37
LYZ-2	38	25	2	13	1.27E−03	0.37
AKR1B10	38	25	2	13	1.27E−03	0.37
SGK2-1	28	35	0	15	6.63E−04	0.37
PIP5K1B-1	28	35	0	15	6.63E−04	0.37
CYP3A5-2	28	35	0	15	6.63E−04	0.37
ELF3-3	28	35	0	15	6.63E−04	0.37
TFF3	13	2	31	32	9.49E−03	0.29

ISSN: 1471-2105