Fig. 3
From: Deciphering the role of RNA structure in translation efficiency
Differential icSHAPE reactivities in high TE and low TE transcripts in mESCs. A in vivo icSHAPE reactivities in the high TE and low TE group. X-axis is the bin index along the entire transcript. Y-axis shows the in vivo icSHAPE reactivities of bins. The high TE and low TE transcripts are highlighted by red and blue curves, respectively. The CDS head of the high TE and low TE transcripts are highlighted by purple and green curves, respectively. B Similar plot as (A), but in vitro. C Significance test of the differences of icSHAPE reactivities between the high TE and low TE transcripts. X-axis is the bin index along the entire transcript (60 bins in total). Y-axis is the -log10(adjusted p-value) of the KS test between the high TE and low TE reactivity in each bin. Red: in vivo; blue: in vitro. The gray horizontal line corresponds to the nominal adjusted p-value cutoff, which is 0.05. D icSHAPE reactivities difference between in vivo and in vitro for high TE and low TE transcripts, respectively. X-axis is the bin index along the entire transcript. Y-axis is in vivo reactivity minus in vitro reactivity. The high TE group and low TE group are highlighted by red and blue curves, respectively. The gray horizontal line indicates zero difference between in vivo and in vitro reactivity