Fig. 3
From: Identification of multiplicatively acting modulatory mutational signatures in cancer
A The modulatory process r inferred for samples in Liver-HCC dominated cluster of PCAWG data shown in Fig. 1. B The corresponding modulatory signature activity histogram. C SBS base mutation type-specific scatter plots of observed vs. predicted (additive + modulatory process model) mutation counts in this cluster. In contrast to model without the modulatory process (Fig. 1D), no systematic deviation is visible