Skip to main content

Table 2 List of significant node pairs that constitute the network

From: iDMET: network-based approach for integrating differential analysis of cancer metabolomics

Pair

 

Platform

 

Cancer type

 

Ratio > 1.2, ratio < 1/1.2

 

Node 1

Node 2

Node 1

Node 2

Node 1

Node 2

Odds

p-value

P17-1

P24-1

GC–MS, LC–MS/MS

GC–MS, LC–MS/MS

Kidney

Kidney

8.95

4.2E − 32

P7-1

P14-7

GC–MS

GC–MS

Colon

Colon

6.71

0.0018

P7-1

14–14

GC–MS

GC–MS

Colon

Colon

6.71

0.0018

P7-1

P14-1

GC–MS

GC–MS

Colon

Colon

6.57

0.0028

P7-1

P14-13

GC–MS

GC–MS

Colon

Colon

6.57

0.0028

P7-1

P14-10

GC–MS

GC–MS

Colon

Colon

6.51

0.0033

P7-2

P14-2

GC–MS

GC–MS

Colon

Colon

6.29

0.0019

P7-1

P14-5

GC–MS

GC–MS

Colon

Colon

6.20

0.0075

P7-2

P14-10

GC–MS

GC–MS

Colon

Colon

6.04

0.0040

P7-2

P14-5

GC–MS

GC–MS

Colon

Colon

5.91

0.0059

P7-1

P14-2

GC–MS

GC–MS

Colon

Colon

5.75

0.0088

P7-1

P14-4

GC–MS

GC–MS

Colon

Colon

5.67

0.0094

P10-2

P18-3

CE-TOFMS

GC–MS, LC–MS

Lung

Prostate

4.81

0.0040

P7-2

P14-1

GC–MS

GC–MS

Colon

Colon

4.58

0.0294

P7-2

P14-13

GC–MS

GC–MS

Colon

Colon

4.58

0.0294

P7-2

P14-14

GC–MS

GC–MS

Colon

Colon

4.46

0.0194

P7-2

P14-7

GC–MS

GC–MS

Colon

Colon

4.17

0.0375

P6-2

P25-1

GC–MS, LC–MS/MS

GC–MS

Kidney

Breast

4.17

0.0492

P16-1

P17-1

LC–MS

GC–MS, LC–MS/MS

Colon

Kidney

 − 4.68

0.0000

P17-1

P18-3

GC–MS, LC–MS/MS

GC–MS, LC–MS

Kidney

Prostate

 − 4.46

0.0021

P6-2

P18-3

GC–MS, LC–MS/MS

GC–MS, LC–MS

Kidney

Prostate

 − 4.29

0.0022

P5-2

P11-7

GC–MS, LC–MS/MS

GC–MS, LC–MS/MS

Lung

Leukemia

 − 4.15

0.0394

P16-2

P17-1

LC–MS

GC–MS, LC–MS/MS

Colon

Kidney

 − 4.08

0.0002

  1. Based on the specified thresholds of the ratios, differential metabolomic profile pairs having remarkable odds ratios and p-values were selected (p < 0.05, odds > 4). The odds ratio shows a high positive (or negative) value if the metabolites were consistently upregulated (or downregulated) in the differential metabolomic profile pair (for details, see Fig. 2, Additional file 1: Table S1, and methods)