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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Establishment and validation of a predictive model of preeclampsia based on transcriptional signatures of 43 genes in decidua basalis and peripheral blood

Fig. 5

Selection of the genes by the logistic least absolute shrinkage and selection operator (LASSO) regression. A, B. LASSO coefficient profiles of the 371 differentially expressed associated genes. Each curve corresponds to one gene; the vertical line is drawn at the value lambda = 0.03087 chosen by tenfold cross-validation. C The network interaction of the 43 gene set inferred using the IMEx Interactome Database. Red nodes indicate the proteins present in the 43 gene set. The size of the node is proportional to the number of connections. The large nodes represent a few highly concentrated hub nodes, while most small nodes have only a few connections

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BMC Bioinformatics

ISSN: 1471-2105

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