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Table 10 Top 10 predicted targets of olanzapine by ADA-GRMFC on the NR dataset

From: Graph regularized non-negative matrix factorization with prior knowledge consistency constraint for drug–target interactions prediction

Rank

Name of targets

ID

Evidence

1

5-hydroxytryptamine receptor 2A

hsa3356

KEGG &DrugBank

2

adrenoceptor alpha 1A

hsa148

KEGG &DrugBank

3

5-hydroxytryptamine receptor 2C

hsa3358

KEGG &DrugBank

4

adrenoceptor alpha 2A

hsa150

KEGG

5

adrenoceptor alpha 1D

hsa146

KEGG

6

dopamine receptor D2

hsa1813

KEGG &DrugBank

7

adrenoceptor alpha 2B

hsa151

KEGG

8

adrenoceptor alpha 1B

hsa147

KEGG &DrugBank

9

5-hydroxytryptamine receptor 1D

hsa3352

DrugBank

10

5-hydroxytryptamine receptor 1B

hsa3351

DrugBank

  1. Known interactions are in bold