Fig. 3
From: GBCdb: RNA expression landscapes and ncRNA–mRNA interactions in gallbladder carcinoma
A primary analysis of experimentally supported GBC-associated proteins and overview of GBCdb. A PPI network of the screened experimentally supported GBC-associated proteins. Two clusters were identified, and the detailed score distributions are presented. B The correlations of genes and drugs (top of 24 drugs) based on Cancer Cell Line Encyclopedia (CCLE). *Indicates significant correlations (|correlation coefficient|> 0.3 and FDR < 0.05). C Expressions of significantly differentially expressed genes in GSE76633 (|log2FC|> 1.2 and padj < 0.05). D Overview of GBCdb. The left panel shows an example of a searched mRNA, and the right panel shows a total mRNA-miRNA-lncRNA network. All these RNAs are significantly dysregulated. In each miRNA-mRNA or miRNA-lncRNA pair, one is significantly up-regulated while the other is significantly down-regulated in tumor samples. RNA expression patterns can be queried in different datasets and corresponding experimentally supported data are also provided in different molecular levels