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Table 3 Clinical pathological parameters for RCC patients after univariate and multivariate analyses

From: FDC-SP as a diagnostic and prognostic biomarker and modulates immune infiltrates in renal cell carcinoma

Characteristics

Total (N)

Univariate analysis

Multivariate analysis

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

T stage

539

    

 T1

278

Reference

   

 T2

71

1.515 (0.908–2.526)

0.112

0.177 (0.035–0.903)

0.037

 T3

179

3.354 (2.373–4.742)

 < 0.001

0.432 (0.117–1.601)

0.209

 T4

11

10.829 (5.467–21.451)

 < 0.001

0.446 (0.094–2.122)

0.311

N stage

257

    

 N0

241

Reference

   

 N1

16

3.453 (1.832–6.508)

 < 0.001

1.433 (0.492–4.169)

0.509

M stage

506

    

 M0

428

Reference

   

 M1

78

4.389 (3.212–5.999)

 < 0.001

0.429 (0.040–4.615)

0.485

Age

539

    

 <  = 60

269

Reference

   

 > 60

270

1.765 (1.298–2.398)

 < 0.001

1.661 (1.052–2.623)

0.029

Histologic grade

531

    

 G1

14

Reference

   

 G2

235

7,510,356.751 (0.000-Inf)

0.994

3,980,595.814 (0.000-Inf)

0.996

 G3

207

14,161,426.542 (0.000-Inf)

0.993

6,771,509.761 (0.000-Inf)

0.996

 G4

75

38,204,822.146 (0.000-Inf)

0.993

7,718,630.236 (0.000-Inf)

0.996

Pathologic stage

536

    

 Stage I

272

Reference

   

 Stage II

59

1.207 (0.650–2.241)

0.551

4.543 (0.707–29.173)

0.111

 Stage III

123

2.705 (1.800–4.064)

 < 0.001

3.972 (0.986–16.005)

0.052

 Stage IV

82

6.692 (4.566–9.808)

 < 0.001

27.692 (2.086–367.529)

0.012

Gender

539

    

 Female

186

Reference

   

 Male

353

0.930 (0.682–1.268)

0.648

  

FDCSP

539

    

 Low

269

Reference

   

 High

270

1.809 (1.325–2.468)

 < 0.001

0.991 (0.621–1.582)

0.970

  1. The significance of bold is P < 0.05