Table 5 Case study 3: prediction of experimentally validated IL-13 inducing peptides
From: iIL13Pred: improved prediction of IL-13 inducing peptides using popular machine learning classifiers
S.No | Peptide sequence | Proposed study | Proposed study | Jain et al. [19] | Jain et al. [19] |
|---|---|---|---|---|---|
Score | Prediction | Score | Prediction | ||
1 | KKGELALFYLQEQINHFEEKPTKEMKDKIVAEMDTI | 0.95 | IL-13 | 0.98 | IL-13 |
2 | GYFADPKDPHKFYICSNWEAVHKDCPGNTRWNEDEETCT | 0.94 | IL-13 | 0.92 | IL-13 |
3 | PDEVRRMMAEIDTDGDGFISFDEFTDFARANRGLVKDVSKIF | 0.94 | IL-13 | 0.92 | IL-13 |
4 | TNACSINGNAPAEIDLRQMRTVTPIRMQGGCGSCWAFSGVA | 0.94 | IL-13 | 0.92 | IL-13 |
5 | AAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLGSVTP | 0.94 | IL-13 | 0.96 | IL-13 |
6 | PEGFPFKYVKDRVDEVDHTNFKYNYSVIEGGPIGDTLEKISNEIK | 0.94 | IL-13 | 0.86 | IL-13 |
7 | FGISNYCQIYPPNANKIREALAQPQRYCR | 0.94* | IL-13 | 0.94* | IL-13 |
8 | ATESAYLAYRNQSLDLAEQELVDCASQHGCHGDTIPRGIEYIQ | 0.93 | IL-13 | 0.90 | IL-13 |
9 | DTPQDIADRERGGSFDTNGDGKISSGGSTDGDGFISFDEFTDFARANRGLVKDV | 0.93 | IL-13 | 0.98 | IL-13 |
10 | LHLSEQYKELEKTKSKELKEQILRELTIGENFMKGAL | 0.93 | IL-13 | 0.95 | IL-13 |
11 | EVDVPGIDPNACHYMKCPLVKGQQYDIKYTWIVPKIAPKSEN | 0.93* | IL-13 | 0.93* | IL-13 |
12 | REQSCRRPNAQRFGISNYCQIYPPNVNKIREALAQTH | 0.93 | IL-13 | 0.90 | IL-13 |
13 | WMHHNMDLI | 0.93 | IL-13 | 0.53 | IL-13 |
14 | KLQCVDLHV | 0.92 | IL-13 | 0.96 | IL-13 |
15 | LFPKVAPQAISSVENIEGNGGPGTIKKISFPEGFPFKYVKDRVDE | 0.92 | IL-13 | 0.90 | IL-13 |
16 | VHDDVVSMEYDLAYKLGDLHPNTHVISDIQDFVVEL | 0.92 | IL-13 | 0.96 | IL-13 |
17 | LSVGWISGQY | 0.92 | IL-13 | 0.31 | IL-13 |
18 | DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA | 0.91 | IL-13 | 0.82 | IL-13 |
19 | IYSTVASSL | 0.90 | IL-13 | 0.98 | IL-13 |
20 | NYEEAQTLSK | 0.85 | IL-13 | 0.82 | IL-13 |
21 | AKFVAAWTLKAAA | 0.78 | IL-13 | 0.72 | IL-13 |
22 | PITAKAIAASVG | 0.55 | IL-13 | 0.36 | IL-13 |
23 | EAALAAFAKIAE | 0.54 | IL-13 | 0.64 | IL-13 |
24 | EAALAKFAAIAE | 0.54 | IL-13 | 0.66 | IL-13 |
25 | EAALKAFAAIAE | 0.54 | IL-13 | 0.59 | IL-13 |
26 | LDVVCAMIEGAQG | 0.53 | IL-13 | 0.49 | IL-13 |
27 | SLGWATLVGEITAGNLLHTR | 0.53 | IL-13 | 0.27 | IL-13 |
28 | PRFIAVGYVDDTE | 0.51 | IL-13 | 0.11 | IL-13 |
29 | YDGSVVAINP | 0.46 | IL-13 | 0.24 | IL-13 |
30 | GTCLESLRRYLELGKERL | 0.40 | IL-13 | 0.38 | IL-13 |
31 | LVRYWISAFP | 0.34 | IL-13 | 0.58 | IL-13 |
32 | GPTHLFQPSLVLDMAKVLLD | 0.30 | IL-13 | 0.35 | IL-13 |
33 | IVDTISDFRAAIANYHYDAD | 0.29 | IL-13 | 0.26 | IL-13 |
34 | QNGRWISRDP | 0.27 | IL-13 | 0.21 | IL-13 |
35 | NNSYECDIPIGAGICASYQ | 0.24 | IL-13 | 0.17 | IL-13 |
36 | FARQAVWLRE | 0.24 | IL-13 | 0.33 | IL-13 |
37 | YTTGAVRQIFGDYKTTICGK | 0.23 | IL-13 | 0.08 | IL-13 |
38 | AENPRMEPRARWMEREGPEYW | 0.22 | IL-13 | 0.07 | IL-13 |
39 | IYNRNIVNRL | 0.20 | IL-13 | 0.19 | IL-13 |
40 | WNRKRISNCVADYSVLYNS | 0.20 | IL-13 | 0.13 | IL-13 |
41 | MEVGWYRSSFSRVVHLYRNGK | 0.19 | IL-13 | 0.10 | IL-13 |
42 | QAPEYRGRTELLKDAIGEGKVTLRI | 0.18 | IL-13 | 0.09 | IL-13 |
43 | GYKDGNEYI | 0.18 | IL-13 | 0.23 | IL-13 |
44 | NKIQDKVTIDGY | 0.18 | IL-13 | 0.06 | IL-13 |
45 | AALALLLLDRLNQLE | 0.16 | IL-13 | 0.07 | IL-13 |
46 | FEELIKFSFHTNVLEDNIGY | 0.15 | IL-13 | 0.20 | IL-13 |
47 | LRHNPGGPSSAVPLLLSYFQ | 0.14 | IL-13 | 0.07 | IL-13 |
48 | MESGEWVIKE | 0.12 | IL-13 | 0.10 | IL-13 |
49 | SGIPYIISYLHPGNTILHVD | 0.10 | IL-13 | 0.11 | IL-13 |
50 | SGIPYVISYLHPGNTVMHVD | 0.10 | IL-13 | 0.05 | Non-IL-13 |
51 | HWFVTQRNFYEPQII | 0.09 | IL-13 | 0.11 | IL-13 |
52 | HPGNTILHVDTIYNRPSNTT | 0.09 | IL-13 | 0.07 | IL-13 |
53 | VGGNYNYLYRLFRKSNLKP | 0.09 | IL-13 | 0.21 | IL-13 |
54 | FNNFTVSFWLRVPKVSASHLE | 0.09 | IL-13 | 0.08 | IL-13 |
55 | MEVGWYRSPFSRVVHLYRNGK | 0.08 | IL-13 | 0.07 | IL-13 |
56 | DESTESETEQAF | 0.07 | IL-13 | 0.04 | Non-IL-13 |
57 | MEVGWYRPPFSRVVHLYRNGK | 0.07* | IL-13 | 0.07* | IL-13 |
58 | HSLGKLLGRPDKF | 0.07 | IL-13 | 0.12 | IL-13 |
59 | AGFKGEQGPKGEP | 0.06 | IL-13 | 0.03 | Non-IL-13 |
60 | HSLGKWLGHPDKF | 0.06 | Non-IL-13 | 0.04 | Non-IL-13 |
61 | ISQAVHAAHAEINEAGR | 0.05 | Non-IL-13 | 0.03 | Non-IL-13 |
62 | NCTFEYVSQPFLMDL | 0.04 | Non-IL-13 | 0.05 | Non-IL-13 |
63 | NAGFNSNRANSSRSS | 0.03 | Non-IL-13 | 0.02 | Non-IL-13 |
64 | QYIKANSKFIGITEL | 0.03 | Non-IL-13 | 0.02 | Non-IL-13 |
65 | VHFFKNIVTPRTPPPSQGKGR | 0.03 | Non-IL-13 | 0.08 | IL-13 |
66 | KIYNRNIVNRLLGD | 0.02 | Non-IL-13 | 0.05 | Non-IL-13 |
67 | NTWTTCQSIAFPSK | 0.01 | Non-IL-13 | 0.02 | Non-IL-13 |
68 | NFSQILPDPSKPSKR | 0.01 | Non-IL-13 | 0.01 | Non-IL-13 |
| Â | AVERAGE | 0.424 | Â | 0.389 | Â |