Table 9 Block model simulation results: 200 phenotype 0, 100 phenotype 1 subjects
From: Automatic block-wise genotype-phenotype association detection based on hidden Markov model
Method | Sensitivity | Specificity | MCC |
|---|---|---|---|
HMM 0.1 | 0.6765 | 0.9545 | 0.6279 (0.3620) |
HMM 0.15 | 0.7257 | 0.9868 | 0.7178 (0.2885) |
HMM 0.2 | 0.7371 | 0.9896 | 0.7398 (0.2716) |
Bonferroni | 0.0196 | 1.000 | 0.0831 (0.1037) |
FDR | 0.1609 | 0.9843 | 0.1903 (0.0846) |
SKAT | 0.0883 | 0.9884 | 0.0798 (0.1983) |
SKATO | 0.3554 | 0.9741 | 0.3370 (0.3386) |
Burden | 0.3940 | 0.9670 | 0.3926 (0.3317) |
wtest | 0.6602 | 0.9540 | 0.6022 (0.2458) |