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Fig. 3 | BMC Bioinformatics

Fig. 3

From: A mixed-effects stochastic model reveals clonal dominance in gene therapy safety studies

Fig. 3

a Simulated trajectories. b Scatterplot between the clone-specific true parameters \(\pmb{\theta} _{true}\) and the conditional expectation \(E_{\pmb {u}\vert \Delta \pmb {y}; \hat{\pmb {\psi }}}[\pmb {u}]\). c Clonal pie-charts where each clone k is identified with a pie whose slices are lineage-specific and weighted according to Eq. (16). The diameter of the k-th pie is proportional to the Euclidean 2-norm of \(\pmb {w}_k\), as defined in Eq. (17). Each row refers to specific values of synthetic noise variance \(\sigma ^2\)

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